About CancerCureToday.com

Cancer Cure Today is an initiative by DR. Ranga Rao Rangaraju – MBBS, MD (Internal Medicine), DM (Medical Oncology)

Welcome to the cancercuretoday.com website of Dr Ranga Rao Rangaraju, the reputed cancer specialist (medical oncologist) in Gurugram. He is extensively trained in management of all cancers with great skills and deals with chemotherapy, hormonal therapy, targeted therapy and the recently introduced immunotherapy. The range of solid tumours managed by him include, breast cancers, gynaecological cancers, lung cancers, gastrointestinal tumours, hepatobiliary tumours, urological tumours, head and neck tumours, lymphomas, and hematological cancers but he is Best Cancer Doctor in Delhi NCR

He is working as Chairman of Paras Cancer Centre, at C 1, Sushant Lok phase 1, Gurugram 122002

International Cancer Treatment

Cancer Cure today welcomes International Patients from all corners of the world.

Cancer Cure Today, a website, is solely focused on creating on awareness on all aspects of cancer especially the prevention, treatment and cure of cancer. I have used the available knowledge and the experience gained over the last few decades to the content for this website and I am hopeful you will it useful. In many past years, I and our team had the opportunity of providing personalised cancer care and second opinions to many international patients and their physicians. In this challenging COVID times, it has not been possible for long travels for many, and we would like to extend the ‘second opinion/advice’ service online to make it accessible to those patients. We welcome all patients from all over the world to avail this service till they are able to travel and subsequently meet them in person to serve them with utmost care and compassion, providing a personalised cancer care.

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Cancer Cure Today is an initiative by DR. Ranga Rao Rangaraju – MBBS, MD (Internal Medicine), DM (Medical Oncology)

Cancer is a group of many different diseases that have some important things in common. Cancer affects our cells, the body’s basic unit of life. Cancerous cell is larger in size than normal cell, multiplies uncontrollably, spreads to other organs and is independent of the normal regulations of the body. To understand more about cancer, it is helpful to know how normal cells become cancerous. In short it can be said that alteration or loss of good genes and development of many bad genes results in cancer.

The body is made up of many types of cells, which live under well-regulated conditions. Most of the functions of the cell are carried out under the orders of “genes”, which are DNA particles inside the nucleus of the cell. Some of the important functions of the cell are – multiplication, growth and repair and these are carried out under control of regulatory “genes”. These genes ensure that the required function is carried out only when required and stops when not required, something like ‘on’ and ‘off’ buttons. They also ensure that the normal cells do not encroach on other organs and respect cellular boundaries. For example, when there is an injury of any part of the body, the damaged tissues send a signal to the cells in the neighbourhood (the button is on!) and the cells start multiplying and on completion of healing the signals are sent again (the button is off!) and the cells stop multiplying.

When there is an alteration (mutation) of these regulatory genes, the cells behave in a different manner and when many such abnormal mutant genes (oncogenes) accumulate in the cell over the period of time, the end result is cancerous growth. The situation is like having wrong buttons on and right buttons off. The cells grow in size and number; multiply uncontrollably without any purpose. They spread to other organs and start growing there too. During their growth they can destroy the organs, impair their functions, steal the nutrition, produce many harmful substances that can lead to wasting of the body and ultimately death. This is the cancer that troubles the patient.

Cells can become cancerous if some important regulatory genes are lost completely from the cell. Other genes undergo mutations without any check (like the bad guys being active in absence of policemen) and form ‘oncogenes’ and the end result is the cancerous growth. Thus one can conclude that these regulatory genes when present normally have eliminate the mutations occurring in the body before they can cause any harm. Since these genes can prevent cancer they are appropriately referred to as ‘tumour suppressor genes’. Many such genes exist in the body and their loss results in specific cancers. They may be responsible for familial cancers, as well as faster growth in some cancers, and thus believed be very important in the genesis of cancer. It is possible that such genes prevent cancerous growth in many of those heavy smokers who do not suffer cancer.

So cancer is the end result of many genetic events as multiple mutations and loss of tumour suppressor genes.

The formation of cancer cell (carcinogenesis) is the end result of a long complicated process and multiple genetic events. Unlike infections, it may take long time, upto few years in some cancers to develop.  What brings about the change in the genes (mutations) in the cell is not fully known. Some of the factors are inheritance of wrong genes, loss of tumour suppressor genes, exposure to radiation, tobacco use, viral infections, wrong dietary habits, dietary chemicals, use of alcohol, lack of exercise, obesity, hormones etc. In some cancers nulliparity is a predisposing factor, while in others sexual promiscuity, multiple sexual partners and multiparity are responsible. Long-term exposure to these factors leads to mutations and then the cancer. It has been well documented that incidence of cancer in the country has been on the increase during the process of industrialisation due to changed life-styles and exposure to many known factors. After many years the incidence of cancer comes down on implementation of well-planned cancer control programmes.

When the mass of extra cells grows to a visible size is referred to as ‘tumour’. Tumours can be benign or malignant. Benign tumours are not cancer. They often can be removed and, in most cases, they do not come back. Cells in benign tumours do not spread to other parts of the body. Most important, benign tumours are rarely a threat to life. Apart from removal they do not require any other form of treatment.

Malignant tumours are cancerous growth that we have been talking about. Cells in malignant tumours are abnormal and divide without control or order. These cancer cells can invade and destroy the tissue around them. Cancer cells can also break away from the original site of a malignant tumour and enter the bloodstream or lymphatic system vessels (the two systems of vessels that bathe and feed all of the body’s organs). This process, called ‘metastasis’, is how cancer spreads from the original tumour to form new tumours in other parts of the body. This spread determines the ‘stage’ of cancer. An advanced stage refers to when the spread is to distant organs and early stage means the spread has not taken place.

 

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