Dr R Ranga Rao has a very good experience of research and clinical trials in cancers. While in the Armed forces, he carried out a research project on chronic myeloid leukemia (CML) and a coworker in many other projects. He had won several medals & awards during his service for his academic work. Also he was awarded the prestigious Vishist Seva Medal (VSM), for his exceptional devotion to duty and contribution to oncology in Armed forces.
Dr (Col) R Ranga Rao, VSM has a great aptitude for research in cancer. He began his career in oncology with a review of testicular cancer as his thesis and brought out some new and intriguing facts about these cancers. In armed forces he pursued his research in chronic myeloid leukemia (cml) with the help of Dr Seema Nandi of National Virology Institute, Pune and carried AFMRC research project on bcr-abl oncogene estimation while on treatment with alpha interferon. For this he was awarded Lt Gen R S Hoon award. He had several other research projects and clinical trials to his credit.
- Phase II Multicentric randomised double blinded study with Buparlisib and paclitaxel vs placebo and paclitaxel in patients with platinum pre-treated recurrent or metastatic head and neck squamous cell carcinoma.
- Phase II study of weekly cisplatin and paclitaxel plus cetuximab as induction therapy in advanced squamous cell carcinoma head and neck(SCCHN).
- TROPIC : Multicentric trial (Sanofi) : Phase III randomized trial: Cabazitaxel vs mitozantron in docetaxel pretreated patients of HRPC.
- Impact of Chemotherapy in Non Seminomatous germ Cell Tumour at Cancer Institute Chennai. (Thesis topic submitted to Dr MGR Medical University for DM Medical Oncology) 1993.
- Concurrent administration of Alpha Interferon in moderate doses with hydroxyurea in chronic and accelerated phase of CML. Carried 11 out in 1993-1997. Evaluated the responses with clinical, haematological criteria and molecular responses (bcr-abl) using RT PCR technique. The project was jointly carried out with National Institute of Virology, Pune.
- Impact of use of prophylactic G-CSF in paediatric ALL with moderately intense Chemotherapy and cost benefit analysis in 1995-98. Found it to be cost effective in terms of less hospitalization and antibiotics.
- Combination chemotherapy (FOG-Infusional 5 FU, Oxaliplatin and Gemcitabine) in advanced Gall bladder and Pancreatic cancers.
- Induction weekly regime chemotherapy with TIP followed by Surgery or Concurrent Chemoradiotherapy in stage IIA and IIB carcinoma cervix.
- Thalidomide in refractory Solid Tumours (Published)
- Weekly paclitaxel, Cisplatin and gefitinib in recurrent head and Neck malignancies.(PG Student Topic)
- Cetuximab and weekly chemotherapy in recurrent and metastatic head and neck cancers.(Published)
- Gefitinib in recurrent head and neck cancers.(published) 13. Impact of Chemotherapy in Non Seminomatous germ Cell Tumour at Cancer Institute Chennai. (Thesis topic submitted to Dr MGR Medical University for DM Medical Oncology) 1993.